Disrupted Kisspeptin Signaling in GnRH Neurons Leads to Hypogonadotrophic Hypogonadism

Landmark studies have shown that mutations in kisspeptin and the kisspeptin receptor (Kiss1r) result in reproductive dysfunction in humans and genetically altered mouse models. However, because kisspeptin and its receptor are present in target cells of the central and peripheral reproductive axis, t...

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Bibliografiske detaljer
Main Authors: Novaira, Horacio J., Sonko, Momodou L., Hoffman, Gloria, Koo, Yongbum, Ko, Chemyong, Wolfe, Andrew, Radovick, Sally
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896637/
https://ncbi.nlm.nih.gov/pubmed/24422632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1319
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