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Serum decreases the size of Metafectene-and Genejammer-DNA complexes but does not affect significantly their transfection activity in SCCVII murine squamous cell carcinoma cells

Cationic liposome-DNA (lipoplexes) or polymer-DNA (polyplexes) complexes have been used to deliver therapeutic genes, both in vitro and in vivo. However, gene transfer by these non-viral vectors is usually inhibited by biological milieu. A relatively high efficiency of transfection could be achieved...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Konopka, Krystyna, Overlid, Nathan, Nagaraj, Anitha C., Düzgüneş, Nejat
Formato: Artigo
Idioma:Inglês
Publicado em: Versita 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276004/
https://ncbi.nlm.nih.gov/pubmed/16847564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-006-0015-5
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