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Inhibition of HIV-1 Env-Mediated Cell-Cell Fusion by Lectins, Peptide T-20, and Neutralizing Antibodies

BACKGROUND: Broadly cross-reactive, neutralizing human monoclonal antibodies, including 2F5, 2G12, 4E10 and IgG1 b12, can inhibit HIV-1 infection in vitro at very low concentrations. We examined the ability of these antibodies to inhibit cell-cell fusion between Clone69TRevEnv cells induced to expre...

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Detalhes bibliográficos
Main Authors: Yee, Michael, Konopka, Krystyna, Balzarini, Jan, Düzgüneş, Nejat
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109660/
https://ncbi.nlm.nih.gov/pubmed/21660189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874357901105010044
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