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Inhibitor-2 induced M-phase arrest in Xenopus cycling egg extracts is dependent on MAPK activation

The evolutionarily-conserved protein phosphatase 1 (PP1) plays a central role in dephosphorylation of phosphoproteins during the M phase of the cell cycle. We demonstrate here that the PP1 inhibitor inhibitor-2 protein (Inh-2) induces an M-phase arrest in Xenopus cycling egg extracts. Interestingly,...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Khandani, Arian, Mohtashami, Mahmood, Camirand, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: SP Versita 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275968/
https://ncbi.nlm.nih.gov/pubmed/21956525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-011-0030-z
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