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Synthesis and Evaluation of Troponoids as a New Class of Antibiotics

[Image: see text] Novel antibiotics are urgently needed. The troponoids [tropones, tropolones, and α-hydroxytropolones (α-HT)] can have anti-bacterial activity. We synthesized or purchased 92 troponoids and evaluated their antibacterial activities against Staphylococcus aureus, Escherichia coli, Aci...

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Détails bibliographiques
Publié dans:ACS Omega
Auteurs principaux: Cao, Feng, Orth, Cari, Donlin, Maureen J., Adegboyega, Patrick, Meyers, Marvin J., Murelli, Ryan P., Elagawany, Mohamed, Elgendy, Bahaa, Tavis, John E.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2018
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275967/
https://ncbi.nlm.nih.gov/pubmed/30533576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01754
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