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17β-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/Akt pathway

Osteoarthritis (OA) is the most common cause of musculoskeletal pain and disability. The importance of chondrocytes in the pathogenesis of OA is unequivocal. 17β-estradiol (E2) has a potential protective effect against OA. However, the mechanism of E2 in OA chondrocytes remains unclear. In this stud...

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Bibliografiske detaljer
Udgivet i:Cell Mol Biol Lett
Main Authors: Huang, Jia Gu, Xia, Chun, Zheng, Xin Peng, Yi, Ting Ting, Wang, Xiao Yong, Song, Gang, Zhang, Bing
Format: Artigo
Sprog:Inglês
Udgivet: SP Versita 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275964/
https://ncbi.nlm.nih.gov/pubmed/21847664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-011-0023-y
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