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β-ecdysterone alleviates osteoarthritis by activating autophagy in chondrocytes through regulating PI3K/AKT/mTOR signal pathway

Purpose: To investigate the therapeutic effects of β-ecdysterone on osteoarthritis (OA) and the underlying mechanism. Methods: OA model was established on rats by injecting MIA. ELSA was used to determine the concentration of IL-1β, IL-6, NO and TNF-α in the chondrocytes and cartilage tissues. Immun...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Tang, Yanghua, Mo, Yafeng, Xin, Dawei, Zeng, Linru, Yue, Zhenshuang, Xu, Canda
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724317/
https://ncbi.nlm.nih.gov/pubmed/33312358
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