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Differences in the degree of inhibition of NDP reductase by chemical inactivation and by the thermosensitive mutation nrdA101 in Escherichia coli suggest an effect on chromosome segregation

NDP reductase activity can be inhibited either by treatment with hydroxyurea or by incubation of an nrdA (ts) mutant strain at the non-permissive temperature. Both methods inhibit replication, but experiments on these two types of inhibition yielded very different results. The chemical treatment imm...

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Bibliografski detalji
Izdano u:Cell Mol Biol Lett
Glavni autori: Riola, José, Guarino, Estrella, Guzmán, Elena C., Jiménez-Sánchez, Alfonso
Format: Artigo
Jezik:Inglês
Izdano: Versita 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275884/
https://ncbi.nlm.nih.gov/pubmed/17124544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-006-0060-0
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