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Defective Ribonucleoside Diphosphate Reductase Impairs Replication Fork Progression in Escherichia coli

The observed lengthening of the C period in the presence of a defective ribonucleoside diphosphate reductase has been assumed to be due solely to the low deoxyribonucleotide supply in the nrdA101 mutant strain. We show here that the nrdA101 mutation induces DNA double-strand breaks at the permissive...

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Detalhes bibliográficos
Main Authors: Guarino, Estrella, Jiménez-Sánchez, Alfonso, Guzmán, Elena C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855873/
https://ncbi.nlm.nih.gov/pubmed/17322311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01632-06
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