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Combined therapy with osimertinib and afatinib in a lung adenocarcinoma patient with EGFR T790M mutation and multiple HER2 alterations after resistance to icotinib: A case report
Acquired resistance inevitably occurs after initial treatment with first‐generation EGFR‐tyrosine kinase inhibitors (TKIs). Several mechanisms have been identified, including EGFR T790M mutation and HER2 amplification. Herein, we present the case of a patient who progressed on first‐generation EGFR‐...
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| Publicado no: | Thorac Cancer |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons Australia, Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6275817/ https://ncbi.nlm.nih.gov/pubmed/30295016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.12889 |
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