Population-level rhythms in human skin with implications for circadian medicine

Skin is the largest organ in the body and serves important barrier, regulatory, and sensory functions. The epidermal layer shows rhythmic physiological responses to daily environmental variation (e.g., DNA repair). We investigated the role of the circadian clock in the transcriptional regulation of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wu, Gang, Ruben, Marc D., Schmidt, Robert E., Francey, Lauren J., Smith, David F., Anafi, Ron C., Hughey, Jacob J., Tasseff, Ryan, Sherrill, Joseph D., Oblong, John E., Mills, Kevin J., Hogenesch, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275491/
https://ncbi.nlm.nih.gov/pubmed/30377266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809442115
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