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Population-level rhythms in human skin with implications for circadian medicine

Skin is the largest organ in the body and serves important barrier, regulatory, and sensory functions. The epidermal layer shows rhythmic physiological responses to daily environmental variation (e.g., DNA repair). We investigated the role of the circadian clock in the transcriptional regulation of...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Wu, Gang, Ruben, Marc D., Schmidt, Robert E., Francey, Lauren J., Smith, David F., Anafi, Ron C., Hughey, Jacob J., Tasseff, Ryan, Sherrill, Joseph D., Oblong, John E., Mills, Kevin J., Hogenesch, John B.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275491/
https://ncbi.nlm.nih.gov/pubmed/30377266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809442115
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