Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis

Lipocalin-2 is a constituent of the neutrophil secondary granules and is expressed de novo by macrophages and epithelium in response to inflammation. Lipocalin-2 acts in a bacteriostatic fashion by binding iron-loaded siderophores required for bacterial growth. Mycobacterium tuberculosis (M.tb) prod...

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Vydáno v:Front Immunol
Hlavní autoři: Dahl, Sara Louise, Woodworth, Joshua S., Lerche, Christian Johann, Cramer, Elisabeth Præstekjær, Nielsen, Pia Rude, Moser, Claus, Thomsen, Allan Randrup, Borregaard, Niels, Cowland, Jack Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275245/
https://ncbi.nlm.nih.gov/pubmed/30534124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02717
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