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Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis
Lipocalin-2 is a constituent of the neutrophil secondary granules and is expressed de novo by macrophages and epithelium in response to inflammation. Lipocalin-2 acts in a bacteriostatic fashion by binding iron-loaded siderophores required for bacterial growth. Mycobacterium tuberculosis (M.tb) prod...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2018-11-01
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Colecção: | Frontiers in Immunology |
Assuntos: | |
Acesso em linha: | https://www.frontiersin.org/article/10.3389/fimmu.2018.02717/full |
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