Sub-Toxic Human Amylin Fragment Concentrations Promote the Survival and Proliferation of SH-SY5Y Cells via the Release of VEGF and HspB5 from Endothelial RBE4 Cells

Human amylin is a 37-residue peptide hormone (hA1-37) secreted by β-cells of the pancreas and, along with insulin, is directly associated with type 2 diabetes mellitus (T2DM). Amyloid deposits within the islets of the pancreas represent a hallmark of T2DM. Additionally, amylin aggregates have been f...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Caruso, Giuseppe, Fresta, Claudia G., Lazzarino, Giacomo, Distefano, Donatella A., Parlascino, Paolo, Lunte, Susan M., Lazzarino, Giuseppe, Caraci, Filippo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274958/
https://ncbi.nlm.nih.gov/pubmed/30463298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113659
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