IL-24 Promotes Apoptosis through cAMP-Dependent PKA Pathways in Human Breast Cancer Cells

Interleukin 24 (IL-24) is a tumor-suppressing protein, which inhibits angiogenesis and induces cancer cell-specific apoptosis. We have shown that IL-24 regulates apoptosis through phosphorylated eukaryotic initiation factor 2 alpha (eIF2α) during endoplasmic reticulum (ER) stress in cancer. Although...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Persaud, Leah, Mighty, Jason, Zhong, Xuelin, Francis, Ashleigh, Mendez, Marifer, Muharam, Hilal, Redenti, Stephen M., Das, Dibash, Aktas, Bertal Huseyin, Sauane, Moira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274865/
https://ncbi.nlm.nih.gov/pubmed/30424508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113561
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