Intravenous Delivery of piggyBac Transposons as a Useful Tool for Liver-Specific Gene-Switching

Hydrodynamics-based gene delivery (HGD) is an efficient method for transfecting plasmid DNA into hepatocytes in vivo. However, the resulting gene expression is transient, and occurs in a non-tissue specific manner. The piggyBac (PB) transposon system allows chromosomal integration of a transgene in...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Nakamura, Shingo, Ishihara, Masayuki, Watanabe, Satoshi, Ando, Naoko, Ohtsuka, Masato, Sato, Masahiro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274756/
https://ncbi.nlm.nih.gov/pubmed/30400245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113452
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