Metformin Hydrochloride-Loaded PLGA Nanoparticle in Periodontal Disease Experimental Model Using Diabetic Rats

Evidence shows that metformin is an antidiabetic drug, which can exert favorable anti-inflammatory effects and decreased bone loss. The development of nanoparticles for metformin might be useful for increased therapeutic efficacy. The aim of this study was to evaluate the effect of metformin hydroch...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Pereira, Aline de Sousa Barbosa Freitas, Brito, Gerly Anne de Castro, Lima, Maria Laura de Souza, da Silva Júnior, Arnóbio Antônio, Silva, Emanuell dos Santos, de Rezende, Adriana Augusto, Bortolin, Raul Hernandes, Galvan, Maria, Pirih, Flávia Q., de Araújo Júnior, Raimundo Fernandes, de Medeiros, Caroline Addison Carvalho Xavier, Guerra, Gerlane Coelho Bernando, de Araújo, Aurigena Antunes
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274734/
https://ncbi.nlm.nih.gov/pubmed/30404181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113488
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