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Auto-antibodies to IgE and FceRI and the Natural Variability of SYK Expression in Basophils
BACKGROUND: Secretion from human basophils and mast cells requires the activity of SYK but expression of SYK is highly variable in the general population and this variability predicts the magnitude of IgE-mediated secretion. One known mechanism of modulating SYK expression in human basophils is aggr...
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| Pubblicato in: | J Allergy Clin Immunol |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6274596/ https://ncbi.nlm.nih.gov/pubmed/29859965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.05.019 |
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