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Backbone Resonance Assignments of Complexes of Apo Human Calmodulin Bound to IQ Motif Peptides of Voltage-Dependent Sodium Channels Na(V)1.1, Na(V)1.4 and Na(V)1.7

Human voltage-gated sodium (Na(V)) channels are critical for initiating and propagating action potentials in excitable cells. Nine isoforms have different roles but similar topologies, with a pore-forming α-subunit and auxiliary transmembrane β-subunits. Na(V) pathologies lead to debilitating condit...

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Detalhes bibliográficos
Publicado no:Biomol NMR Assign
Main Authors: Isbell, Holly M., Kilpatrick, Adina M., Lin, Zesen, Mahling, Ryan, Shea, Madeline A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274588/
https://ncbi.nlm.nih.gov/pubmed/29728980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-018-9824-5
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