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Backbone Resonance Assignments of Complexes of Apo Human Calmodulin Bound to IQ Motif Peptides of Voltage-Dependent Sodium Channels Na(V)1.1, Na(V)1.4 and Na(V)1.7
Human voltage-gated sodium (Na(V)) channels are critical for initiating and propagating action potentials in excitable cells. Nine isoforms have different roles but similar topologies, with a pore-forming α-subunit and auxiliary transmembrane β-subunits. Na(V) pathologies lead to debilitating condit...
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| Veröffentlicht in: | Biomol NMR Assign |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6274588/ https://ncbi.nlm.nih.gov/pubmed/29728980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-018-9824-5 |
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