Backbone Resonance Assignments of Complexes of Apo Human Calmodulin Bound to IQ Motif Peptides of Voltage-Dependent Sodium Channels Na(V)1.1, Na(V)1.4 and Na(V)1.7

Human voltage-gated sodium (Na(V)) channels are critical for initiating and propagating action potentials in excitable cells. Nine isoforms have different roles but similar topologies, with a pore-forming α-subunit and auxiliary transmembrane β-subunits. Na(V) pathologies lead to debilitating condit...

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Veröffentlicht in:Biomol NMR Assign
Hauptverfasser: Isbell, Holly M., Kilpatrick, Adina M., Lin, Zesen, Mahling, Ryan, Shea, Madeline A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274588/
https://ncbi.nlm.nih.gov/pubmed/29728980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-018-9824-5
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