LC-MS/MS Analysis and Pharmacokinetics of Sodium (±)-5-Bromo-2-(α-hydroxypentyl) Benzoate (BZP), an Innovative Potent Anti-Ischemic Stroke Agent in Rats

A rapid, sensitive and selective liquid chromatography-triple quadrupole mass spectrometry (LC-MS/MS) method was developed and validated for the simultaneous determination of sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate (BZP) and its active metabolite 3-butyl-6-bromo-1(3H)-isobenzofuranone (Br-NB...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Tian, Xin, Liu, Bingjie, Zhang, Yuhai, Li, Hongmeng, Wei, Jingyao, Wang, Gaoju, Chang, Junbiao, Qiao, Hailing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274500/
https://ncbi.nlm.nih.gov/pubmed/27092484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21040501
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