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Identification and Characterisation of the Antimicrobial Peptide, Phylloseptin-PT, from the Skin Secretion of Phyllomedusa tarsius, and Comparison of Activity with Designed, Cationicity-Enhanced Analogues and Diastereomers

Antimicrobial peptides belonging to the phylloseptin family are mainly found in phyllomedusine frogs. These peptides not only possess potent antimicrobial activity but exhibit low toxicity against eukaryotic cells. Therefore, they are considered as promising drug candidates for a number of diseases....

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Опубликовано в: :Molecules
Главные авторы: Gao, Yitian, Wu, Di, Xi, Xinping, Wu, Yue, Ma, Chengbang, Zhou, Mei, Wang, Lei, Yang, Mu, Chen, Tianbao, Shaw, Chris
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273899/
https://ncbi.nlm.nih.gov/pubmed/27918477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21121667
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