Docetaxel-Loaded Self-Assembly Stearic Acid-Modified Bletilla striata Polysaccharide Micelles and Their Anticancer Effect: Preparation, Characterization, Cellular Uptake and In Vitro Evaluation

Poorly soluble drugs have low bioavailability after oral administration, thereby hindering effective drug delivery. A novel drug-delivery system of docetaxel (DTX)-based stearic acid (SA)-modified Bletilla striata polysaccharides (BSPs) copolymers was successfully developed. Particle size, zeta pote...

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Опубликовано в: :Molecules
Главные авторы: Guan, Qingxiang, Sun, Dandan, Zhang, Guangyuan, Sun, Cheng, Wang, Miao, Ji, Danyang, Yang, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273633/
https://ncbi.nlm.nih.gov/pubmed/27918445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21121641
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