In vitro and in vivo evaluation of docetaxel-loaded stearic acid-modified Bletilla striata polysaccharide copolymer micelles

Bletilla striata polysaccharides (BSPs) have been used in pharmaceutical and biomedical industry, the aim of the present study was to explore a BSPs amphiphilic derivative to overcome its application limit as poorly water-soluble drug carriers due to water-soluble polymers. Stearic acid (SA) was sel...

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Bibliographic Details
Published in:PLoS One
Main Authors: Guan, Qingxiang, Zhang, Guangyuan, Sun, Dandan, Wang, Yue, Liu, Kun, Wang, Miao, Sun, Cheng, Zhang, Zhuo, Li, Bingjin, Lv, Jiayin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363891/
https://ncbi.nlm.nih.gov/pubmed/28334044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173172
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