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Solubilization Behavior of Polyene Antibiotics in Nanomicellar System: Insights from Molecular Dynamics Simulation of the Amphotericin B and Nystatin Interactions with Polysorbate 80

Amphotericin B (AmB) and Nystatin (Nys) are the drugs of choice for treatment of systemic and superficial mycotic infections, respectively, with their full clinical potential unrealized due to the lack of high therapeutic index formulations for their solubilized delivery. In the present study, using...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Mobasheri, Meysam, Attar, Hossein, Rezayat Sorkhabadi, Seyed Mehdi, Khamesipour, Ali, Jaafari, Mahmoud Reza
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273564/
https://ncbi.nlm.nih.gov/pubmed/26712721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21010006
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