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Solubilization Behavior of Polyene Antibiotics in Nanomicellar System: Insights from Molecular Dynamics Simulation of the Amphotericin B and Nystatin Interactions with Polysorbate 80

Amphotericin B (AmB) and Nystatin (Nys) are the drugs of choice for treatment of systemic and superficial mycotic infections, respectively, with their full clinical potential unrealized due to the lack of high therapeutic index formulations for their solubilized delivery. In the present study, using...

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Vydáno v:Molecules
Hlavní autoři: Mobasheri, Meysam, Attar, Hossein, Rezayat Sorkhabadi, Seyed Mehdi, Khamesipour, Ali, Jaafari, Mahmoud Reza
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273564/
https://ncbi.nlm.nih.gov/pubmed/26712721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21010006
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