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Applications of (19)F-NMR in Fragment-Based Drug Discovery
(19)F-NMR has proved to be a valuable tool in fragment-based drug discovery. Its applications include screening libraries of fluorinated fragments, assessing competition among elaborated fragments and identifying the binding poses of promising hits. By observing fluorine in both the ligand and the t...
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| Pubblicato in: | Molecules |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6273323/ https://ncbi.nlm.nih.gov/pubmed/27438818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21070860 |
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