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Gold Nanocluster Decorated Polypeptide/DNA Complexes for NIR Light and Redox Dual-Responsive Gene Transfection

Endo/lysosomal escape and subsequent nuclear translocation are recognized as the two major challenges for efficient gene transfection. Herein, nuclear localization signal (NLS) peptide sequences and oligomeric lysine sequences were crosslinked via disulfide bonds to obtain glutathione (GSH) reducibl...

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Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Lei, Qi, Hu, Jing-Jing, Rong, Lei, Cheng, Han, Sun, Yun-Xia, Zhang, Xian-Zheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273015/
https://ncbi.nlm.nih.gov/pubmed/27556436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21081103
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