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Gold Nanocluster Decorated Polypeptide/DNA Complexes for NIR Light and Redox Dual-Responsive Gene Transfection

Endo/lysosomal escape and subsequent nuclear translocation are recognized as the two major challenges for efficient gene transfection. Herein, nuclear localization signal (NLS) peptide sequences and oligomeric lysine sequences were crosslinked via disulfide bonds to obtain glutathione (GSH) reducibl...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lei, Qi, Hu, Jing-Jing, Rong, Lei, Cheng, Han, Sun, Yun-Xia, Zhang, Xian-Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273015/
https://ncbi.nlm.nih.gov/pubmed/27556436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21081103
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