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Prediction of Placental Barrier Permeability: A Model Based on Partial Least Squares Variable Selection Procedure

Assessing the human placental barrier permeability of drugs is very important to guarantee drug safety during pregnancy. Quantitative structure–activity relationship (QSAR) method was used as an effective assessing tool for the placental transfer study of drugs, while in vitro human placental perfus...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zhang, Yong-Hong, Xia, Zhi-Ning, Yan, Li, Liu, Shu-Shen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272791/
https://ncbi.nlm.nih.gov/pubmed/25961165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20058270
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