Pretreatment with Relaxin Does Not Restore NO-Mediated Modulation of Calcium Signal in Coronary Endothelial Cells Isolated from Spontaneously Hypertensive Rats

We demonstrated that in coronary endothelial cells (RCEs) from normotensive Wistar Kyoto rats (WKY), the hormone relaxin (RLX) increases NO production and reduces calcium transients by a NO-related mechanism. Since an impairment of the NO pathway has been described in spontaneously hypertensive rats...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Nistri, Silvia, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Zanardelli, Matteo, Bani, Daniele, Failli, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272299/
https://ncbi.nlm.nih.gov/pubmed/26016544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20069524
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