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Different Apoptotic Pathways Activated by Oxaliplatin in Primary Astrocytes vs. Colo-Rectal Cancer Cells

Oxaliplatin-based chemotherapy improves the outcomes of metastatic colorectal cancer patients. Its most significant and dose-limiting side effect is the development of a neuropathic syndrome. The mechanism of the neurotoxicity is unclear. The limited knowledge about differences existing between neur...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zanardelli, Matteo, Micheli, Laura, Nicolai, Raffaella, Failli, Paola, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394482/
https://ncbi.nlm.nih.gov/pubmed/25761243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16035386
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