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In vivo and in vitro assessment of mirtazapine pharmacokinetics in cats with liver disease
BACKGROUND: Liver disease (LD) prolongs mirtazapine half‐life in humans, but it is unknown if this occurs in cats with LD and healthy cats. HYPOTHESIS/OBJECTIVES: To determine pharmacokinetics of administered orally mirtazapine in vivo and in vitro (liver microsomes) in cats with LD and healthy cats...
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| Pubblicato in: | J Vet Intern Med |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6272035/ https://ncbi.nlm.nih.gov/pubmed/30307637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.15237 |
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