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CopA3 Peptide Prevents Ultraviolet-Induced Inhibition of Type-I Procollagen and Induction of Matrix Metalloproteinase-1 in Human Skin Fibroblasts

Ultraviolet (UV) exposure is well-known to induce premature aging, which is mediated by matrix metalloproteinase-1 (MMP-1) activity. A 9-mer peptide, CopA3 (CopA3) was synthesized from a natural peptide, coprisin, which is isolated from the dung beetle Copris tripartitus. As part of our continuing s...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kim, Dong-Hee, Kim, Han-Hyuk, Kim, Hyeon-Jeong, Jung, Hyun-Gug, Yu, Jae-Myo, Lee, Eun-Su, Cho, Yong-Hun, Kim, Dong-In, An, Bong-Jeun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271994/
https://ncbi.nlm.nih.gov/pubmed/24853614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19056407
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