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The Plant Decapeptide OSIP108 Can Alleviate Mitochondrial Dysfunction Induced by Cisplatin in Human Cells

We investigated the effect of the Arabidopsis thaliana-derived decapeptide OSIP108 on human cell tolerance to the chemotherapeutic agent cisplatin (Cp), which induces apoptosis and mitochondrial dysfunction. We found that OSIP108 increases the tolerance of HepG2 cells to Cp and prevents Cp-induced c...

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Publicat a:Molecules
Autors principals: Spincemaille, Pieter, Alborzinia, Hamed, Dekervel, Jeroen, Windmolders, Petra, van Pelt, Jos, Cassiman, David, Cheneval, Olivier, Craik, David J., Schur, Julia, Ott, Ingo, Wölfl, Stefan, Cammue, Bruno P. A., Thevissen, Karin
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271462/
https://ncbi.nlm.nih.gov/pubmed/25244288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190915088
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