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pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy

Avidin and avidin-like proteins are widely used in numerous techniques since the avidin-biotin interaction is known to be very robust and reliable. Within this study, we investigated this bond at the molecular level under harsh conditions ranging from very low to very high pH values. We compared avi...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Köhler, Melanie, Karner, Andreas, Leitner, Michael, Hytönen, Vesa P., Kulomaa, Markku, Hinterdorfer, Peter, Ebner, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271454/
https://ncbi.nlm.nih.gov/pubmed/25153869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190812531
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