Synthesis, Cytotoxicity and Mechanistic Evaluation of 4-Oxoquinoline-3-carboxamide Derivatives: Finding New Potential Anticancer Drugs

As part of a continuing search for new potential anticancer candidates, we describe the synthesis, cytotoxicity and mechanistic evaluation of a series of 4-oxoquinoline-3-carboxamide derivatives as novel anticancer agents. The inhibitory activity of compounds 10–18 was determined against three cance...

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Pubblicato in:Molecules
Autori principali: Forezi, Luana da S. M., Tolentino, Nathalia M. C., de Souza, Alessandra M. T., Castro, Helena C., Montenegro, Raquel C., Dantas, Rafael F., Oliveira, Maria E. I. M., Silva, Floriano P., Barreto, Leilane H., Burbano, Rommel M. R., Abrahim-Vieira, Bárbara, de Oliveira, Riethe, Ferreira, Vitor F., Cunha, Anna C., Boechat, Fernanda da C. S., de Souza, Maria Cecília B. V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271384/
https://ncbi.nlm.nih.gov/pubmed/24858098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19056651
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