Synthesis, Cytotoxicity and Mechanistic Evaluation of 4-Oxoquinoline-3-carboxamide Derivatives: Finding New Potential Anticancer Drugs

As part of a continuing search for new potential anticancer candidates, we describe the synthesis, cytotoxicity and mechanistic evaluation of a series of 4-oxoquinoline-3-carboxamide derivatives as novel anticancer agents. The inhibitory activity of compounds 10–18 was determined against three cance...

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Publicat a:Molecules
Autors principals: Forezi, Luana da S. M., Tolentino, Nathalia M. C., de Souza, Alessandra M. T., Castro, Helena C., Montenegro, Raquel C., Dantas, Rafael F., Oliveira, Maria E. I. M., Silva, Floriano P., Barreto, Leilane H., Burbano, Rommel M. R., Abrahim-Vieira, Bárbara, de Oliveira, Riethe, Ferreira, Vitor F., Cunha, Anna C., Boechat, Fernanda da C. S., de Souza, Maria Cecília B. V.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271384/
https://ncbi.nlm.nih.gov/pubmed/24858098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19056651
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