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Synthesis of Novel 2-(Substituted amino)alkylthiopyrimidin-4(3H)-ones as Potential Antimicrobial Agents

5-Alkyl-6-(substituted benzyl)-2-thiouracils 3a,c were reacted with (2-chloroethyl) diethylamine hydrochloride to afford the corresponding 2-(2-diethylamino)ethylthiopyrimidin-4(3H)-ones 4a,b. Reaction of 3a–c with N-(2-chloroethyl)pyrrolidine hydrochloride and/or N-(2-chloroethyl)piperidine hydroch...

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Dades bibliogràfiques
Publicat a:Molecules
Autors principals: Attia, Mohamed I., El-Emam, Ali A., Al-Turkistani, Abdulghafoor A., Kansoh, Amany L., El-Brollosy, Nasser R.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271362/
https://ncbi.nlm.nih.gov/pubmed/24378967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19010279
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