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Synthesis and Antimicrobial Activity of Some Novel 5-Alkyl-6-Substituted Uracils and Related Derivatives

6-Chloro-5-ethyl-, n-propyl- and isopropyluracils 5a-c were efficiently prepared from the corresponding 5-alkybarbituric acids 3a-cvia treatment with phosphorus oxychloride and N,N-dimethylaniline to yield the corresponding 5-alkyl-2,4,6-trichloro-pyrimidines 4a-c, which were selectively hydrolyzed...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Al-Turkistani, Abdulghafoor A., Al-Deeb, Omar A., El-Brollosy, Nasser R., El-Emam, Ali A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264406/
https://ncbi.nlm.nih.gov/pubmed/21654581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16064764
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