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A Novel Synthesis of the Oxazolidinone Antithrombotic Agent Rivaroxaban
A facile synthetic route of rivaroxaban has been developed. Using commercially available (R)-epichlorohydrin and bromobenzene as the starting materials, rivaroxaban was obtained in 39% overall yield using a Goldberg coupling as the key step. The synthetic route represents a convenient procedure for...
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| Udgivet i: | Molecules |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6271174/ https://ncbi.nlm.nih.gov/pubmed/25237754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190914999 |
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