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Combined Dynamic Light Scattering and Raman Spectroscopy Approach for Characterizing the Aggregation of Therapeutic Proteins

Determination of the physicochemical properties of protein therapeutics and their aggregates is critical for developing formulations that enhance product efficacy, stability, safety and manufacturability. Analytical challenges are compounded for materials: (1) that are formulated at high concentrati...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Lewis, E. Neil, Qi, Wei, Kidder, Linda H., Amin, Samiul, Kenyon, Stacy M., Blake, Steven
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271152/
https://ncbi.nlm.nih.gov/pubmed/25514228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191220888
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