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Combined Dynamic Light Scattering and Raman Spectroscopy Approach for Characterizing the Aggregation of Therapeutic Proteins

Determination of the physicochemical properties of protein therapeutics and their aggregates is critical for developing formulations that enhance product efficacy, stability, safety and manufacturability. Analytical challenges are compounded for materials: (1) that are formulated at high concentrati...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Lewis, E. Neil, Qi, Wei, Kidder, Linda H., Amin, Samiul, Kenyon, Stacy M., Blake, Steven
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271152/
https://ncbi.nlm.nih.gov/pubmed/25514228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191220888
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