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Combined Dynamic Light Scattering and Raman Spectroscopy Approach for Characterizing the Aggregation of Therapeutic Proteins

Determination of the physicochemical properties of protein therapeutics and their aggregates is critical for developing formulations that enhance product efficacy, stability, safety and manufacturability. Analytical challenges are compounded for materials: (1) that are formulated at high concentrati...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lewis, E. Neil, Qi, Wei, Kidder, Linda H., Amin, Samiul, Kenyon, Stacy M., Blake, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271152/
https://ncbi.nlm.nih.gov/pubmed/25514228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191220888
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