Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids

Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively. Structures of the products were elucidated by spectroscopic analysis. The synthesized compounds were e...

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Pubblicato in:Molecules
Autori principali: Otero, Elver, Vergara, Sebastián, Robledo, Sara M., Cardona, Wilson, Carda, Miguel, Vélez, Ivan D., Rojas, Carlos, Otálvaro, Felipe
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271011/
https://ncbi.nlm.nih.gov/pubmed/25170948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190913251
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