Cinchona Alkaloid Derivative-Catalyzed Enantioselective Synthesis via a Mannich-Type Reaction and Antifungal Activity of β-Amino Esters Bearing Benzoheterocycle Moieties

An efficient synthesis of highly functionalized chiral β-amino ester derivatives containing benzothiophene and benzothiazole moieties is developed by a Mannich-type reaction using a cinchona alkaloid-derived thiourea catalyst. The desired products were obtained in good yields and high enantioselecti...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Xiao, Han, Wu, Fang, Shi, Li, Chen, Zhiwei, Su, Shihu, Tang, Chenghao, Wang, Hongtao, Li, Zhining, Li, Meichuan, Shi, Qingcai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270673/
https://ncbi.nlm.nih.gov/pubmed/24694652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19043955
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