Flavonoids with M(1) Muscarinic Acetylcholine Receptor Binding Activity

Muscarinic acetylcholine receptor-active compounds have potential for the treatment of Alzheimer’s disease. In this study, a series of natural and synthetic flavones and flavonols was assayed in vitro for their ability to inhibit radioligand binding at human cloned M(1) muscarinic receptors. Several...

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Veröffentlicht in:Molecules
Hauptverfasser: Swaminathan, Meyyammai, Chee, Chin Fei, Chin, Sek Peng, Buckle, Michael J. C., Rahman, Noorsaadah Abd., Doughty, Stephen W., Chung, Lip Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270666/
https://ncbi.nlm.nih.gov/pubmed/24979399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19078933
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