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Design, Synthesis and Antitumor Activity of Novel 4-Methyl-(3'S,4'S)-cis-khellactone Derivatives

An asymmetric synthesis of a series of novel 4-methyl-(3'S,4'S)-cis-khellactone derivatives 3a–o is reported for the first time. Their structures were confirmed by (1)H-NMR, (13)C-NMR and MS. Their cytotoxic activity was evaluated by the MTT assay against three selected human cancer cell l...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ren, Luhui, Du, Xue, Hu, Mengnan, Yan, Chaoqun, Liang, Taigang, Li, Qingshan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270253/
https://ncbi.nlm.nih.gov/pubmed/23567363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18044158
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