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Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues

Naturally occurring anthraquinones, damnacanthal (1) and nordamnacanthal (2) were synthesized with modified reaction steps and investigated for their cytotoxicity against the MCF-7 and K-562 cancer cell lines, respectively. Intermediate analogues 2-bromomethyl-1,3-dimethoxyanthraquinone (5, IC(50) =...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Akhtar, Muhammad Nadeem, Zareen, Seema, Yeap, Swee Keong, Ho, Wan Yong, Lo, Kong Mun, Hasan, Aurangzeb, Alitheen, Noorjahan Banu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269871/
https://ncbi.nlm.nih.gov/pubmed/23966087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules180810042
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