Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues

Naturally occurring anthraquinones, damnacanthal (1) and nordamnacanthal (2) were synthesized with modified reaction steps and investigated for their cytotoxicity against the MCF-7 and K-562 cancer cell lines, respectively. Intermediate analogues 2-bromomethyl-1,3-dimethoxyanthraquinone (5, IC(50) =...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Akhtar, Muhammad Nadeem, Zareen, Seema, Yeap, Swee Keong, Ho, Wan Yong, Lo, Kong Mun, Hasan, Aurangzeb, Alitheen, Noorjahan Banu
Format: Artigo
Langue:Inglês
Publié: MDPI 2013
Sujets:
Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269871/
https://ncbi.nlm.nih.gov/pubmed/23966087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules180810042
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