Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

The increasing number of severe infections with multi-drug-resistant pathogens worldwide highlights the need for alternative treatment options. Given the pivotal role of phagocytes and especially alveolar macrophages in pulmonary immunity, we introduce a new, cell-based treatment strategy to target...

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Pubblicato in:Nat Commun
Autori principali: Ackermann, Mania, Kempf, Henning, Hetzel, Miriam, Hesse, Christina, Hashtchin, Anna Rafiei, Brinkert, Kerstin, Schott, Juliane Wilhelmine, Haake, Kathrin, Kühnel, Mark Philipp, Glage, Silke, Figueiredo, Constanca, Jonigk, Danny, Sewald, Katherina, Schambach, Axel, Wronski, Sabine, Moritz, Thomas, Martin, Ulrich, Zweigerdt, Robert, Munder, Antje, Lachmann, Nico
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269475/
https://ncbi.nlm.nih.gov/pubmed/30504915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07570-7
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