Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

The increasing number of severe infections with multi-drug-resistant pathogens worldwide highlights the need for alternative treatment options. Given the pivotal role of phagocytes and especially alveolar macrophages in pulmonary immunity, we introduce a new, cell-based treatment strategy to target...

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Publicado no:Nat Commun
Principais autores: Ackermann, Mania, Kempf, Henning, Hetzel, Miriam, Hesse, Christina, Hashtchin, Anna Rafiei, Brinkert, Kerstin, Schott, Juliane Wilhelmine, Haake, Kathrin, Kühnel, Mark Philipp, Glage, Silke, Figueiredo, Constanca, Jonigk, Danny, Sewald, Katherina, Schambach, Axel, Wronski, Sabine, Moritz, Thomas, Martin, Ulrich, Zweigerdt, Robert, Munder, Antje, Lachmann, Nico
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269475/
https://ncbi.nlm.nih.gov/pubmed/30504915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07570-7
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